It is common knowledge that many forms of cancer have environmental as well as genetic components: for skin cancer, overexposure to sunlight can trigger its development. Lung cancer, of course, is blamed on smoking for lengthy periods of time. However, sometimes the genetic component can express itself without external assistance. Thus, it is worth noting that the genetic mutations which cause these two afflictions have been pinpointed by geneticists at the Wellcome Trust Sanger Institute of the United Kingdom. The errors are very specific and should be readily detectable with a genetic workup. Something which I find surprising is the …
Pain specialist Dr. Eske Aasvang of Denmark is trying a new compound in clinical pain relief trials: Capsaicin. Yes, the very same compound that makes hot peppers hot, and unwary college students who've never heard of chicken vindaloo before want to shoot themselves. Capsaicin, as it turns out, bonds tightly to the receptors of C-type nerve fibres, which trainsmit status messages to the brain that are interpreted as pain. Those receptors will fire briefly (as anyone who's ever eaten chili can attest to) but then go silent because the nerves will have exhausted their supplies of neurotransmitters. It is expected …
Geneticists at the Massachusetts Institute of Technology have developed a new cell culturing medium that does something amazing: It allows human cells to transform into so-called 'queen' cancer cells, cancer cells that reproduce rapidly and produce mutants that become the actual tumours. Think of them as stem cells that specialize in producing cancers as we normally think of them. Not all malignant cells are capable of doing this, most just sit there and use up resources and oxygen and reproduce, but don't actually break off and spread to other parts of the body. This germ line of cells came about …
