UPDATE (20210214): The game has, in fact, been found (along with its manual) and is playable online at the Internet Archive.
UPDATE (20170120): The game may have been found!
Many years ago, maybe a year after 321 Contact magazine merged with Enter magazine, there was a review of a video game which seemed like it was a tie-in for the movie 2010: The Year We Make Contact. The scenario was that you'd just gained access to the USS Discovery, and you had to repair all of the systems on board the ship to win the game. As I recall, a free hint in the review was that you should repair HAL-9000 first, because he could help you figure out how to fix the rest of the ship. I don't think I ever saw it in a store (then again, it's been over 30 years), nor do I recall reading about it in any of the other Commodore magazines I was reading at the time. It may have been vaporware - an early review copy could have been sent out but it never actually hit the shelves. I've searched for information about this game periodically over the years, and I've had searchbots prowling around looking for information about it as well (even dozens of permutations of likely titles for the work), and none of us have found anything even vaguely talking about it.
Oh, Internet hive-mind... did this ever actually exist? If so, where could I find a copy? And, most importantly, what was the title of the game?
As mentioned above, I think the game in question has been found. Jarandhel succeeded where I kept failing. He was able to determine that the game's title is actually 2010: The Graphic Action Game, and it's not a Commodore title, it's a Colecovision title. The screenshots certainly seem to match what I remember seeing in a magazine, and the game mechanics definitely fit what I recall. The entire game has been described as being one big hacking minigame (warning: TV Tropes link). Chances are there's an abandonware version of it floating around someplace, though I'll need to track down a Colecovision emulator to play it.
I've been sitting on these links for too long and, now that I'm doing some tinkering and additional cleaning up of my website I figured that I'd circle back to this post and update it again. The game 2010: The Graphic Action Game for the Colecovision has been found and is playable on the Internet Archive in your web browser along with its controller overlay card for the Colecovision. It's still under copyright so you can't download the ROM to add to your collection, but it wouldn't surprise me if it's floating around someplace along with the original manual.