HOPE XI - This one went to eleven!

Jul 30, 2016

It's mostly been radio silence for the past couple of days. If you're reading this you've no doubt noticed that Switchboard (one of my constructs) posted the slides from my talk earlier this week. As sophisticated and helpful as she is, Switchboard can't yet pick thoughts out of my wetware to write blog posts. And so, here I am, my primary organic terminal sitting at Windbringer's console keying in notes, saving them, and then going back to turn them into something approaching prose. I've just now had the time to sit down and start writing stuff about HOPE XI, largely because after getting back all hell broke loose at my dayjob (per usual) so I haven't had the time. In point of fact, this writeup will probably happen over the course of a couple of days so it might come off as a bit disjointed.

It felt kind of strange attending this HOPE. I missed the last one two years ago because I was in the middle of moving into our new place on the other coast so I felt a little out of the loop. I missed just about everything that happened there and I keep forgetting to go back and track down the video recordings (so I'll have another part of me do that). It didn't take long to get back into the stride, though. Once you start attending hacker cons regularly it's easy to find how everything comes together, dive in, and get out of it what you're looking for. There weren't many vendors there because HOPE is largely a talks-and-talking to people kind of conference but I did come home with a few things to practice with as I always do. I also went out of my way to not buy another full wardrobe of t-shirts because, even after getting rid of 4/5 of my collection (including, I hasten to add, much of my collection of hacker convention shirts) space in my dresser is still at a premium. So goes the life of a self-admitted clothes horse. I also found one of Seeed Studio's FST-01 ultra-miniature 32-bit computers for sale at a table and snapped it up to use it with NeuG as a random number generator in a few of my projects because my Geiger counter died some months ago, but that's a writeup for another time.

After landing, picking up my luggage, and catching a cab to the hotel I met up with Seele, Genetik, and Nuke, whom I was splitting a hotel room with. I was a bit chagrined when Seele told me that there'd been a booking mixup and the Hotel Pennsylvania had to give us a different room. What I hadn't expected was that they gave us what amounted to a con suite, two full-sized rooms hooked together like a smallish apartment that easily had room for twice as many people as would be staying there. There was sufficient room that we were able to spread out as much as we liked with room left over so sleeping was quite comfortable. I never really got over the jet lag this time so my sleep schedule was all messed up. I may have averaged about four hours of sleep a night all weekend, modulo having to take a nap for a couple of hours on Saturday afternoon because I could neither concentrate on anything nor tune out background noise for very long. Either one left me with a dizzying sense of sensory overload which left me unable to see straight. It also meant that I spent the next couple of days trying to catch up and crashing hard after work for ten to twelve hours, with very strong but fragmentary dreams as my primary long-term memory optimized itself. It was the kind of sleep deprivation that you didn't know you had, as opposed to the kind of sleep deprivation where you know full well you've been awake for three days straight and you feel it in your bones, your fingers, and even in your hair. I didn't make it to all of the talks I wanted to but I did make a point of picking up a couple of DVDs before I left of the ones I really wanted to hit; I also downloaded most of the livestream recordings to watch later on the media box, probably after I get off the road the week after next.

A colleague of mine once remarked that there comes a point where you pretty much level out of most of the stuff that happens at hacker cons and you get more out of interacting with everyone there than you do from attending talks or seminars. I was somewhat skeptical at the time but open-minded about the possibility. Now I'm wondering if that's not the case because, from reading a whitepaper or two and having part of me do a search I can pretty much reconstruct the content of the talk (as verified by actually watching a recording of the talk later) and get the same thing out of it. I definitely came away from most of the discussions I found myself in with new perspectives on a lot of things.

So it goes.

I will be presenting at The Eleventh HOPE.

May 28, 2016

UPDATE: Now that the official HOPE schedule has been published I can say that I'll be speaking in the Noether room on Sunday, 24 July 2016 at 2:00pm EST4EDT.

UPDATE: The Internet Society will be livestreaming video of the talks as they happen. Here's the page listing all of the livestreams.

I found out last weekend (yes, I've been sitting on this - timed posts are the busy blogger's friend) that the talk I submitted for The Eleventh HOPE in July of 2016 was accepted. I will be giving a presentation on Exocortex, my latest work (of mad science), entitled Constructing Exocortices with Huginn and Halo at some point that weekend. I'll be talking about both Huginn (I asked Andrew if he would present with me; he declined because he may not be able to attend HOPE this year (and Andrew, if somehow you can fit it into your busy schedule I'd really like it if you did..)) and Exocortex Halo. To be more specific, I'll be talking a little bit about how they work - what agents do and how they fit together to process information individually to carry out more complex tasks. I'll also be talking about how Halo's constructs send and receive information to and from Huginn to accomplish more sophisticated things (like generate the speech that gets played over a VoIP link or send commands to a personal search engine to index an entire site to sort through later).

This also puts me on the hook to come up with some really off-the-wall but useful stuff to show off. Thankfully I've got several hundred off-the-wall ideas already written down. Now where are my d10's...

When I know where my talk fits into the HOPE schedule I'll post with the specifics. I'd really appreciate it if everyone spread the word about my talk (and thank you in advance if you do).

Catching up on posting.

May 26, 2016

I'd beg the forgiveness of my readers for not posting since early this month, but chances are you've been just as busy as I've been in the past few weeks. Life, work, et cetera, cetera. So, let's get to it.

As I've mentioned once or twice I've been slowly getting an abscessed molar cleaned out and repaired for the past couple of months. It's been slow going, in part because infections require time for the body to fight them off (assisted by antibiotics or not) and, depending on how deep the infection runs it can take a while. Now I can concentrate on getting the molar in front of it, which has long been a thorn in my side, er mouth, worked on. Between being in close proximity to a rather nasty infection and the general stresses applied to molars during everyday life the seal on the crown broke at some point, leaving it somewhat loose and making squishing sounds when I chew. I don't know the extent of the involvement, but from coming home from work wiped out just about every night I'm starting to suspect that something nasty is going on in there also; it's a pattern that I've come to recognize over the years as suggestive of an immune response. There's a good chance that this particular pain-in-the-ass is going to need major repairs and, given how little of the original tooth is left (I lost count of the number of surgeries and root canals performed on it a couple of years ago) I'm pretty much resigned to losing the tooth entirely. I'll probably wind up getting an implant in its place if it does get pulled for the sole reason that it'l prevent the rest of the teeth in my mandible from slowly drifting to the fill in the space. Of course, if I do get an implant I'll try to stick a magnet to it and if it works I'll post the pictures.

Hacking DNA. No, really.

Apr 02, 2016

Last year a new genetic engineering technology called CRISPR - Clustered Regularly Interspaced Short Palindromic Repeats - showed up on my radar at a local conference. Long story short, CRISPR is a highly precise technique for editing DNA in situ which follows from the discovery of short sequences of DNA which allow for precise location of individual genes. It's a fascinating technology; there are even tutorials (archived copy, just in case) online for developing your own guide RNA to implement CRISPR/Cas9. What you might not have known is that CRISPR/Cas9 is being actively studied as a theraputic technique in humans due to the amazing amount of success it's shown in modifying the genomes of other forms of life. At Temple University in Philadelphia, Pennsylvania earlier this year molecular biologists successfully used the technique to hack the DNA of cultured human T-cells in vitro that were infected with HIV and delete the HIV DNA entirely. Moreover, when re-exposed to HIV the hacked T-cells were observed to show immunity to the virus. Further observing the cells after they'd been modified showed that no adverse effects were introduced - the cells were healthy, happy, and just as effective post-CRISPR/Cas9 modification as pre-infection with HIV. The research team's peer-reviewed findings were published in the journal Nature in February of 2016, and the paper went open access online in March of this year.